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Watch Michael Fassbender, Brad Pitt and Javier Bardem in new thriller based on Cormac McCarthy's debut screenplayThe first teaser trailer for highly anticipated Ridley Scott thriller The Counselor, based on novelist Cormac McCarthy's debut screenplay and featuring a stellar cast, has hit the web.The
story of a lawyer (Michael Fassbender) who

gets in over his head when he foolishly dabbles in the drug-trafficking trade, the film also stars Brad Pitt, Javier Bardem, Cameron Diaz and Penélope Cruz.
If Bardem's presence has you recalling his Oscar-winning turn in the Coen brothers' No Country for Old Men, itself based on a McCarthy novel, the teaser's ominous tone only adds to the sense that The Counselor might be a spiritual sequel.That
El Paso road sign suggests the action plays out once again on the Tex-Mex border badlands, and the Spanish actor even sports a bizarre hairdo to match his 70s mullet from the Coens' film. This time around, he's playing a wealthy acquaintance of Fassbender's character, and that spiky black mop is certainly a look that screams playboy. Pitt, meanwhile, portrays a thug who brokers the central drug deal. Diaz plays Bardem's lover, while the latter's real-life wife, Cruz, plays Fassbender's squeeze.McCarthy's
Pulitzer-winning novel The Road was also adapted by Hollywood for a 2009 John Hillcoat film starring Viggo Mortensen and Kodi Smit-McPhee as a

father and son negotiating their way through a post-apocalyptic wasteland. No Country for Old Men is said to have begun life as a screenplay, though the film that hit cinemas in 2007 was

based on the Coens' own adapted script.The Counselor is out on 25 October in

the US, with Australia due to follow on 14 November and the UK on 15 November.Ridley ScottFilm adaptationsBrad PittMichael FassbenderJavier BardemPenélope CruzCameron DiazThrillerCormac McCarthyBen Childguardian.co.uk © 2013 Guardian News and Media Limited or its affiliated companies.
All rights reserved. | Use of this content is subject to our Terms & Conditions | More Feeds James UtterbackA look at James Gandolfini’s movies shows there was much more to him

than Tony Soprano.    
There's been a lot written lately on the tragedy of long-term unemployment.
Thanks to the lingering effects of the recession, there are still 4.7 million Americans who have been out of work for at least 27 weeks. And, increasingly, they're becoming unemployable.
Read full article >>     The big idea: Can a for-profit big-game farm in South Africa be the answer to saving the endangered African black rhino? The scenario: In 2011, the

black rhino was close to extinction.
Poaching rhino for the black-market sale of their horns was the primary cause of a precipitous population decline.
At the time, rhino horns could command up to $60,000 a kilogram on the black market.
Read full article >> The victory at Sandy, Utah, was not pretty, but the United States stayed in first place in its World Cup qualifying group.    
Power rankings of the teams left in the Champions League before Friday’s draw in Switzerland. Canceled in 2005 amid complaints that it was debasing political debate, the show that pits a liberal against a conservative is set

to return in the fall.    
Michael Winterbottom doesn't delve too deeply into the psyche of Soho smut and property baron Paul RaymondMichael Winterbottom's The Look of Love is a breezily affectionate if faintly incurious study of Paul Raymond: the Soho nudie-show entrepreneur and property baron who became Britain's richest man.
Dramas about the Soho smut business in its 1960s and 70s heyday tend to look for the dark side, but Winterbottom's movie searches for sympathy in showing Raymond's pitiable, or pitiful relationship with troubled

daughter Debbie, played by Imogen Poots, the Cordelia-figure in whom he hoped to entrust his entire porn kingdom.
The sleazily bequiffed Raymond himself is played by Steve Coogan, who inevitably invests the part with Partridgean irony and comedy – or perhaps rather Cooganian irony and comedy, even doing a few impressions of Sean Connery and Marlon Brando. Coogan always gives a technically accomplished performance, especially when he is playing a version of himself, and as in Winterbottom's The Trip or C**k and Bull Story, his own spiky personality is the performance.
Clearly, Winterbottom did not feel any need to delve too deeply into Raymond's mind or spend much on recreating period detail (the Paramount viewing gallery atop Centre Point did not exist in those days).
This is a shallow but watchable movie, and it nicely conveys the world of semi-respectable Soho porn, sadder and tattier than its sleazier end, with its desperate champagne lunches and dreary afternoon hangovers.Rating:
3/5DramaMichael WinterbottomSteve CooganPeter Bradshawguardian.co.uk
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All rights reserved.
| Use of this content is subject to our Terms & Conditions | More Feeds The suicide rate among middle-age Americans rose 30 percent from 1999 to 2010, with more people now dying of suicide than in car accidents.    
A federal judge yesterday blocked flight attendants at Northwest Airlines from striking over cuts in pay and benefits, ruling that such action could

threaten the struggling carrier's comeback from bankruptcy protection. According to a popular saying, there are four basic food groups: milk chocolate, dark chocolate, white chocolate and chocolate truffles. From the opening minutes to St. Louis' final flurries, Jonathan Quick played every puck with the desperate determination necessary to win the Stanley Cup.     The study doesn't draw specific conclusions, but Dr. Marjorie Jeffcoat, lead author and a professor at the University of Pennsylvania School of Dental Medicine, tells the news service dental care is crucial. Redundancy forced

Dave Pearson from a job he loved in a PRU, but doing a part-time maths degree alongside supply work has injected new energy and purpose into his teachingI qualified as an engineer before I went

into teaching, but a redundancy after my first year of work led me to a bit of a

crossroads.
My mum was a primary school teacher and my micro-niche-finder welding lecturer and they suggested I think about teaching. Design and technology (DT) was a relatively new subject in schools and so with my engineering background and interest in making things I thought this would work.I did a two year teaching degree in Wolverhampton as DT was a shortage subject. Unfortunately, I collapsed a disc in my back while I was in the middle

of the degree and spent most of the last year wearing a whalebone corset, barely able to walk.
Sometimes I even had to lay down on the floor in lectures to take notes and in my first teaching practice I was navigating my way around the classroom looking for the next desk to hold onto. Luckily a spine operation just before my finals sorted my back out.After my degree I had six job interviews but didn't get a job at first so went into supply teaching. Interestingly, I did supply at schools where I'd gone for interviews and ended up being offered jobs I hadn't got at interview. So I'm convinced doing supply work is a great route to getting a job.I
didn't really know I had found my vocation when I started teaching. I was more giving it a shot as an avenue to explore. My first job was at Archbishop Grimshaw school (now John Henry Newman Catholic College) in Chorley Wood and I was really pleased that they paid me two points above the starting scale because of my previous engineering experience and my age. That got me through my NQT year, but then I decided to do supply again.I
got an offer of some work at North Warwickshire Pupil Referral Unit (PRU). I took it for the adventure and as another string to my bow. So I went into working with children with behavioural, emotional and social difficulties (BESD) and special educational needs (SEN) quite lightly. I first walked into the PRU on Monday 8 January 1998, I remember the date because it was such an important turning point in my life.First of all I sat on groups in the unit without being given a specific

role, the same thing happened on Tuesday.
So I went to see the head of the centre to ask what I was actually doing here. I found out the first couple of days were an initiation, as many teachers never came back after the first day. Then I found out about my first pupil, a young man in Nuneaton whose behaviour levels were so bad that no one had been able to engage with him in any way. The centre head told me I could teach him anything I liked as long as you engage him.So
it was a very open brief, before the days when PRUs were monitored and regulated by Ofsted. I went with a project of Roman history but as soon as I walked into the room with the boy and his little brother who had been excluded from primary school, I knew this wasn't going to work at any level. The next time I took my tool box and worked on a project manufacturing working models, and that did the trick.I
met lots of different types of

families in the course of working for North Warwickshire PRU, some were in desperate situations and by the time they saw us there were three generations of problems stacking up. I made it my mission to directly improve the quality of people's lives by going to their homes and put some good into their lives, and try and develop the ability. I started with five tutees who I was supposed to spend one hour a day with.
I was able to tailor specific programmes to meet my pupil's diverse needs and found they responded best when I taught them real life skills.Working with children with serious behavioural, emotional and developmental special needs is very challenging but I realised from the start that it was for me. I've never experienced camaraderie as in the PRU. I was offered a contract after a year and then made a permanent member of staff. Our aim was to start teaching children at home and then

slowly bring them into the PRU in small groups and from there the idea was to go back into mainstream education, but this was very rare.
Teaching some children at home was infinitely better than bringing into the PRU in groups. And if you brought them to the groups too early, it was mayhem. So we were really quite devastated when all the work we'd put in at the PRU wasn't recognised and was trashed by Ofsted who put us in special measures and then ultimately closed us down in 2011 as part of a move to replace PRUs with learning support

units within mainstream schools. I was made redundant and it was an incredibly stressful period.But something happened to me while all this was happening which was a real light in my life and has led to what I'm doing now.
I started teaching maths to some of the groups at the PRU and really enjoyed it.I only had my O-level in maths, so I did an A-level at evening classes at City College Coventry.
I loved it. My maths guru Saeed Vakilpour suggested I did an A-level in further maths before starting a degree and I was still finishing that when I got made redundant so it was a real light shining at a dark time for me.Doing
well at my A-levels really increased my flagging self esteem and I decided to do a degree in maths with the Open University.
I've just completed my first year and am loving it.At
the same time I have been doing some really enjoyable supply work.
I've had a number of assignments at Newbridge Short Stay School in Worcester which has a very similar function to a PRU and I'm mainly focusing fat burning furnace download teaching.
So it's all worked out for me. It just goes to show that even when terrible things happen in your career, you can pick yourself up and find another niche. My plan long term is to teach A-level maths, which I have already been doing

privately. I've also picked up my design and technology teaching again at Newbridge which has a great DT workshop.I love teaching maths. I think it's because it's a subject that I struggled with when I was at school.
I'm not a mathematical genius but I stoically plod through my degree, unpicking it completely so I understand and I think that really helps with

teaching it. I love it seeing the light come on as it did with me.Dave Pearson is a maths teacher (and student) and BESD specialist.This
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All rights reserved. | Use of this content is subject to our Terms & Conditions | More Feeds     With the recent launch of MIT’s Institute for Medical Engineering and Science, MIT News examines research with the potential to reshape medicine and health care through new scientific knowledge, novel treatments and products, better management of medical data, and improvements in health-care delivery.In
the 1970s and 1980s, tissue engineers began working on growing replacement organs for transplantation into patients.
While scientists are still targeting that goal, much of the tissue engineering research at MIT is also focused on creating tissue that can be used in the lab to model human disease and test potential new drugs.This
kind of disease modeling could have a great

impact in the near term, says MIT professor Sangeeta Bhatia, who is developing liver tissue to study hepatitis C and malaria infection. Like other human tissues, liver is difficult to grow outside the human body because cells tend to lose their function when they lose contact with neighboring cells. “The challenge is to grow the cells outside the body while maintaining their function after being removed from their usual microenvironment,” says Bhatia, the John and Dorothy Wilson Professor of Health Sciences and Technology and Electrical Engineering and Computer Science.Bhatia
recently developed the first stem-cell-derived liver tissue model that can be infected with the hepatitis C virus.
She has also designed thin slices of human liver tissue that can be implanted in mice, enabling rapid studies of potential drugs.In a large-scale project recently funded by the Defense Advanced Research Projects Administration, several MIT faculty members are working on a “human-on-a-chip” system that scientists could use to study up to 10 human tissue types at a time. The goal is to create a customizable system of interconnected tissues, grown in small wells on a plate, allowing researchers to analyze how tissues respond to different drugs.“If
they’re developing a drug for Alzheimer’s, they may want to examine the uptake by the intestine, the metabolism by the liver, and the toxicity on heart tissue, brain tissue or lung tissue,” says Linda Griffith, the S.E.T.I.
Professor of Biological

and Mechanical Engineering at MIT and leader of the research team, which also includes scientists from the Charles Stark Draper Laboratory, Zyoxel and MatTek.RegenerationAnother near-term goal for tissue engineers is developing regenerative therapies that help promote wound healing.“Healthy cells

sitting adjacent to diseased tissues can influence the biology of repair and regeneration,” says MIT professor Elazer Edelman, who has developed implantable scaffolds embedded with endothelial cells, which secrete a vast array of proteins that respond to injury. Endothelial cells, normally found lining blood vessels, could help repair damage caused by angioplasty or other surgical interventions; smoke inhalation; and cancer or cardiovascular disease.
The implants are now in clinical trials to treat blood-vessel injuries caused by the needles used to perform dialysis in patients with kidney failure.
Better repair of those injuries could double the time that such patients can stay on dialysis, which is now limited to about three years, says Edelman, the Thomas D. and Virginia W. Cabot Professor of Health Sciences and Technology.Similar
scaffolds could also help heal serious injuries such as smashed bones, which are very difficult to repair. Griffith and George Muschler, an

orthopedic surgeon at the Cleveland Clinic, have developed ceramic scaffolds coated with immature blood cells taken from a patient’s bone marrow, which are now being tested in animals. ReplacementOne of the earliest successes of implantable tissues was the development of artificial skin, which is now commonly used to treat burn victims. Skin was a good place to start because its function is easier to mimic than that of more complex organs such as the heart or liver, says Robert Langer, the David H.
Koch Institute Professor at MIT, who was one of the pioneers of the technology behind

tissue engineering, along with Ioannis Yannas, MIT professor of mechanical engineering.Langer is now working on more complex tissues, such as cardiac-tissue scaffolds that include electronic sensors and a synthetic polymer that could restore vocal-cord function in people who have lost their voices through overuse or other types of damage.One major challenge for designing implantable organs is that the tissues need to include blood vessels that can connect

to the patient’s own blood supply.
In Langer’s lab, researchers are working on inducing blood vessels to form by growing cells on nanopatterned surfaces.In Bhatia’s lab, where tissue-engineering research is evenly divided between modeling diseases and working toward implantable organs, researchers recently developed 3-D liver tissues that include their own network of blood vessels.
In a recent paper in Nature Materials, Bhatia and Christopher Chen of the University of Pennsylvania described how they built the tissues by printing a 3-D network of sugar molecules, google sniper liver tissue around it.
After dissolving the sugar, they stimulated blood vessels to fill in the space left behind. Though still a long-term goal, being able to regenerate new organs could have a great impact on the future of health care, Langer

says. “It’s the kind of thing that can transform society,” he says.
“You can’t have a drug that will grow a new liver or a new heart, so this could be huge.” Sophia Young scores 27 points to lead the Silver Stars to an 86-81 overtime victory over the Monarchs on Monday in a decisive Game 3 of the Western Conference semifinals. John Thompson gets friendly reception during Senate confirmation hearing Sadie Benning’s small show at Callicoon Fine Arts includes paintings, video and a gouache.     Writer and actor Richard O'Brien and composer Richard Hartley remember how

three weeks at the Royal Court turned into a gender-bending 20th Century Fox extravaganzaRichard O'Brien, writer and actorI'd been in Jesus Christ Superstar and Hair, and was starting to think I wouldn't mind seeing a musical that appealed to me, an eternal adolescent.
I loved B-movies, rock'n'roll and glam, so thought I'd do a parody – or homage – to all those things.Then Jim Sharman, the director of Jesus Christ Superstar, asked me to audition for a play at London's Royal Court. There I met Richard Hartley, who was writing its incidental music. One night, Jim brought Richard round to my place, and I sang them

some of my songs, including Science Fiction/Double Feature and Hot Patootie.
Jim thought they'd make a great show and called me afterwards saying: "They've asked me to do another play at the Royal Court and I've agreed – as long as they let me have three weeks' fun upstairs afterwards." So I wrote some more songs and 20 pages of dialogue. I didn't think

it would be a hit. I thought we'd have our three weeks of fun on the Royal Court's upstairs stage then move on.It grew a lot in rehearsals.
I'd written Science Fiction/Double Feature without a musical in mind, but it has the line: "See androids fighting Brad and Janet."
Those names seemed to exemplify a clean-cut, boy-girl relationship.
Brad and Janet needed their own song, so D****t Janet went in.
I think their sexual awakening is something we can all relate to, but it's not just a sexual rites of passage: when their car breaks down and they arrive at the castle, they're leaving the American dream and walking into an uncertain future.It's astonishing that the US movie industry bought into it: there we were with a fringe theatre event that hadn't even gone to the West End, and not only were we allowed to make it into a film, we also all got to star in it – with Jim directing.
The only

imperative from 20th Century Fox was that we include some American actors. That's why Barry Bostwick and Susan Sarandon play Brad and Janet – they were actually an item during filming, too. And then the whole thing nearly got canned when there was a change of head at Fox.
Yet, later, this one movie would keep that studio afloat for three years. It's gone into cinema history. I think you could say it's the No 1 cult classic movie of all time.We filmed in the UK, in an old building next to the Hammer House of Horror studios. It wasn't an actual set: it was an old Victorian gothic revival house a paddock away from the studios that had been used for other films, including the horror movie The Innocents. Listed, gloomy and semi-derelict, with its owner living abroad, it was perfect for us – even if we did have to carry all our lights and technical stuff across the paddock to get to it.The
birthday party for Rocky, the gold-panted creation of Dr Frank N Furter, was the most fun to film, with Peter Hinwood wrapped up in bandages in the laboratory, and all those Transylvanian extras in tailcoats. We finished filming a week before Christmas.
It was freezing on set.
Susan got really ill: at the end, when she sings Wild and Untamed Thing in the pool, she should have been under medical supervision.
She'd had a shocking cold and was shaking with fever, but still she went on.Jim, directing, played pranks on us

throughout filming.
When Eddie's corpse was revealed under the dining table, it came as a real shock: none of us had been aware that it was there apart from Tim Curry – playing Dr Frank

N Furter – because he was the one who had to whip the tablecloth off. Jim wanted a natural reaction.When you consider that, with the exception of Susan, it was the first movie for all of us, we made a pretty good film – and we shot it in six weeks too, without going over budget.
It's flawed, there's no doubt about that. But it's allowed to be a little bit kitsch, I think, and the flaws are part of that quality.
It is rather funny if we see the shadow of a boom mic somewhere.Rocky Horror was probably not the first example of gender-bending on film, but it was the most in-your-face. When Dr Frank N Furter sings "I'm just a sweet transvestite" without any apology, it was empowering for many people. And Janet singing Touch-A Touch-A Touch Me was controversial, too – a girl wanting to be sexual in a let's-get-down-and-do-it way.I like to think I'm more of a lyricist than a dramatist. My favourite Rocky Horror line is: "It's not easy having a good time."
It still makes me laugh. It's pathetic but it does. And the narrator's last verse in Superheroes – "Crawling on the planet's face, some insects called the human race, lost in time, and

lost in space, and meaning" – has a quasi-gravitas I find appealing.You'd think forex growth bot download had enough of it by now, but as long as the band is cooking and the music is rocking and the audience is laughing, I'm happy as a sandboy.Richard Hartley, composerRocky Horror is just Frankenstein with a twist. Except there's no twisting – it's rock'n'roll.
Richard and I listened to the same records when we were growing up, so we just put all the things we loved in. You can hear the influences: a bit of Chuck Berry, and a bit of Rolling Stones in Sweet Transvestite. It's self-indulgent, but the songs aren't pastiche like the ones in Grease.The
space only seated 50 people, but they rolled around with laughter.
I've never thought it was that funny. It was done seriously – this wasn't variety-show camp. Until he was in

costume, Dr Frank N Furter was a serious scientist.
Then, when the high heels came out,

it was liberating for him – and Tim Curry appealed to both sexes.
For the film, they got in a makeup artist, Pierre La Roche, who did Bowie's makeup, but he took so long – about four hours – that Tim just did his own face.Time Warp was added during rehearsals because you need a dance number in a musical. Plus we had to pad it out: the show was only about 40 minutes. It evolved on the fly, all within three weeks. I'd dream up musical arrangements as we rehearsed and, though half the cast were vocally challenged, somehow it fell into place.It was only subversive in the sense that it was raw-edged: the music was like something by a garage band.
For the film, we wanted things to be more gothic, so

we got two musicians in from Procol Harum. It was sweetened for Hollywood, with strings and a brass band, too.
We recorded the backing tracks in four days, and the vocals in a week.
We prerecorded every song except Science Fiction, so what you see is all mimed. It would have been easier and

cheaper if they'd sung live. But the whole film still cost less than $1m.I'm staggered it's such a phenomenon. The film's a bit long, and it's so slow. It wilts after an hour then picks

up again. That might explain why audience participation started to play a big part at screenings – they probably got bored so they started answering back.• For details of The Rocky Horror Show 40th anniversary tour, go to rockyhorror.co.ukMusicalsTheatreRocky
Horror ShowKate Abbottguardian.co.uk © 2013 Guardian News and Media Limited or its affiliated companies. All rights reserved. | Use of this content is subject to our Terms & Conditions | More Feeds German researchers have unveiled evidence suggesting that EU claims, according to which locally-produced rapeseed biodiesel cut back at least 38% of greenhouse gases (GHG) compared with fossil fuels,  are unfounded. More ' Two members of the MIT faculty — Peter Reddien and Aviv Regev — have been named Howard Hughes Medical Institute (HHMI) investigators, bringing the total number of MIT professors who hold the distinction to 18.Selected for their scientific excellence, HHMI investigators remain at their home institutions, but HHMI pays their salaries and funds much of their research. This gives the investigators freedom to explore, change direction in their research and see their ideas through to fruition — even if that process takes many

years. Reddien and Regev will begin their five-year HHMI appointments in September. “HHMI has a very simple mission,” HHMI President Robert Tjian said in announcing the new investigators. “We find the best original-thinking scientists and give them the resources to follow their instincts in discovering basic biological processes that may one day lead to better medical outcomes.
This is a very talented group of scientists. And while we cannot

predict where their research will take them, we’re eager to help them move science

forward.”
Reddien and Regev were among 27 biomedical scientists selected as new HHMI investigators from 1,155 applicants.
HHMI currently supports approximately 330 investigators throughout the country, including 15 Nobel laureates and more than 150

members of the National Academy of Sciences. Peter ReddienPeter Reddien is an associate professor of biology and associate head of MIT’s Department of

Biology.
He is also a member of the Whitehead Institute

for Biomedical Research, an associate member of the Broad Institute and an HHMI Early Career Scientist.Reddien’s
work centers on the study of planaria, flatworms that have regenerative abilities. His lab seeks to identify and understand the molecular and cellular mechanisms that control these worms’ regeneration. His group discovered that planaria are equipped with stem cells that have the capacity to become any type of cell in their bodies — and that these cells create new tissue during regeneration.
Reddien continues to investigate the sources of planaria’s regenerative powers.
His insights may lead to new understanding of the genes and pathways that control tissue repair and stem cells in humans. His work may also help reveal the limits of the human body to regenerate lost or injured tissue.
Aviv RegevAviv Regev is an associate professor of biology at MIT.
She is also a core faculty member and director of the Klarman Cell Observatory at the Broad Institute and an HHMI Early Career Scientist.Regev uses computational and experimental approaches to investigate how molecular networks that regulate gene activity respond to genetic and environmental changes — in the short term and over millennia.
She has developed, among other things, techniques to analyze how yeast genes and regulatory networks have changed over 300 million years and how circuits change as immune cells respond to pathogens. Additionally, her lab is using advanced experimental techniques, such as inserting genes into cells with silicon nanowires, to chart the molecular circuitry of T cells. Her algorithms are used in labs around the world to analyze gene expression data

and other information.
Inside Andrew Carmellini’s newest restaurant.    
MINNEAPOLIS -- Airlines are rushing to add new regional jets with first-class seats, roomier cabins and, in some cases, hot

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